Niacin is the most effective agent currently available for increasing levels of high-density lipoprotein. Minimally clinically significant. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The armour interacts with both the iron and magnesium making the thyroid med less absorbed, so separate these vitamins from your armour by at least 4 hrs. When NIASPAN 2000 mg and lovastatin 40 mg were co-administered, NIASPAN increased lovastatin Cmax and AUC by 2% and 14%, respectively, and decreased lovastatin acid Cmax and AUC by 22% and 2%, respectively. Check all prescription and nonprescription medicine labels carefully since vitamins/dietary supplements may also contain niacin or niacinamide (nicotinamide). 2,48 in the chronic illness interactions niacin crestor and drug is immobilization. Some interactions may increase your risk of side effects (such as flushing), while others can cause an unsafe drop in blood pressure. Minor Drug Interaction. Niacin has been used for decades to treat dyslipidaemic disorders. The other major interaction is atenolol and niacin. However, they also have the potential for drug interactions with many common over-the-counter and prescription medications and some supplements. These are only a few of the possible drug interactions, which is why it is very important that you discuss your medical history and all medications—prescription or otherwise—with your healthcare team before taking a statin. When taken together, bleeding time should be closely monitored. The combination of niacin and HMG-CoA reductase inhibitors (statins) may increase the risk of myopathies or rhabdomyolysis. There are 6 disease interactions with niacin which include: coronary artery disease; hepatotoxicity; hypotension; peptic ulcer disease; hyperglycemia; hyperuricemia It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. Acarbose: (Moderate) Niacin (nicotinic acid) interferes with glucose metabolism and can result in hyperglycemia. Niacin Interactions. Niacin is the most effective agent currently available for increasing levels of high-density lipoprotein. Related Multimedia Click on an icon to view. Less … Because of the described effects of niacin on the coagulation cascade and the possibility for pharmacokinetic interactions, there is a potential for synergistic coagulopathy when combined with warfarin therapy. Information for this minor interaction is only available at a professional reading level. Avoid combinations; the risk of the interaction outweighs the benefit. If you're taking niacin and have gout, you might need to take more of this gout medicine to control your gout. Select one or more newsletters to continue. DRUG INTERACTIONS. DRUG INTERACTIONS. Thirty additional rats … Niacin warnings Allergy warning. Learn about drug interactions between atorvastatin oral and niacin oral and use the RxList drug interaction checker to check drug combinations. Drug Saf. Acarbose: (Moderate) Niacin (nicotinic acid) interferes with glucose metabolism and can result in hyperglycemia. ... All generic drug interactions for niacin oral (lists will include brand and generic names): 14 serious drug interactions; Typically, the interaction occurs at doses of 1 g/day or greater of niacin. For clinical details see professional interaction data. Patients should avoid taking niacin if they suffer from liver disease, a stomach ulcer, or bleeding. These animals also received a 32% ethanol solution. Seventy animals were submitted to a four-week depletion period during which they were fed a corn grits diet with no niacin, vitamin B6 or zinc added. Finally, probucol may have potential drug interactions with antidysrhythmics, tricyclic antidepressants and phenothiazines. Beta blockers,. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Highly clinically significant. Niacin Interactions. 4 This translates to an increased risk of drug interactions. Diabetes Medications. A total of 96 drugs are known to interact with Patients should also avoid taking niacin alongside colestipol (Colestid) or cholestyramine (Locholest, Prevalite, and Questran). Drug Interactions Fluvastatin. 9,10 Pharmacists are likely to encounter this interaction, since statins are among the most commonly prescribed medications. Lovastatin. These types of drugs, herbs and supplements reduce blood clotting. Moderately clinically significant. atorvastatin, simvastatin, Lipitor, fenofibrate, rosuvastatin, Crestor, ezetimibe, gemfibrozil, TriCor, Lopid. Moreover, significant improvements in cardiovascular outcomes in niacin treated patients have been demonstrated. niacin. These products interact with niacin, preventing its full absorption. Patients should also avoid taking niacin alongside colestipol (Colestid) or cholestyramine (Locholest, Prevalite, and Questran). These may increase your risk of side effects if taken together. The use of niacin with statins should be recommended only if the benefits of lipid-lowering outweigh the risks of myopathies and rhabdomyolysis. Niacin did not affect fluvastatin pharmacokinetics [see DRUG INTERACTIONS]. Anticoagulant drugs . There are 2 alcohol/food interactions with niacin. How to use Niacin-Inositol. View interaction reports for niacin and the medicines listed below. 2. Medications for diabetes (Antidiabetes drugs) interacts with NIACIN AND NIACINAMIDE (VITAMIN B3) Long-term use of niacin and niacinamide might increase blood sugar. Continue to take other medications to lower your cholesterol as directed by your doctor. Nicotinic acid (niacin) may have potential drug interactions with high dose aspirin (acetylsalicylic acid), uricosuric agents (such as sulfapyrazone) and alcohol (ethanol). An interaction is when a substance changes the way a drug works. Moreover, significant improvements in cardiovascular outcomes in niacin treated patients have been demonstrated. If you’re one of these medications, then you should take them to six hours before taking niacin. Alcohol. Consult your pharmacist or physician. The interaction of niacin, vitamin B6 and zinc was studied in Wistar rats. Changes in glycemic control can usually be corrected through modification of hypoglycemic therapy. Vagal tone and feeding behavior, activity, color, mucus production, smooth muscle within the vt. Cardiomegaly and a patho- logical conditions, 51,42 in these cases. This drug interaction can lead to abnormally low blood pressure and increases the risk of... Alpha blockers,. Patients should avoid taking niacin if they suffer from liver disease, a stomach ulcer, or bleeding. Generally, over-the-counter niacin … We would like to show you a description here but the site won’t allow us. Anticoagulant and anti-platelet drugs, herbs and supplements. Niacin did not affect fluvastatin pharmacokinetics [see DRUG INTERACTIONS]. Niacin has been used for decades to treat dyslipidaemic disorders. Call 911 or go to the nearest emergency room if you... Alcohol interaction warning. If you believe you are experiencing an interaction, contact a healthcare provider immediately. Ding RW, Kolbe K, Merz B, de Vries J, Weber E, Benet Z. Pharmacokinetics of nicotinic acid-salicylic acid interaction. Show all medications in the database that may interact with niacin. Drug Interactions Fluvastatin. Drug interactions. Changes in glycemic control can usually be corrected through modification of hypoglycemic therapy. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Possible interactions include: 1. Niacin drug interactions. Niacin oral tablet can interact with other medications, vitamins, or herbs you may be taking. Some products that may interact with this drug include: "blood thinners" (such as acenocoumarol, warfarin). Significant Drug Interactions Certain Antibiotics . If you also take certain other drugs to lower cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take niacin at least 4 to 6 hours before or after taking these medications. The occurrence of rhabdomyolysis is increased in patients treated with statins (HMG-CoA reductase inhibitors). There are 96 drug interactions with Nicotinic Acid (niacin) Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). Common niacin side effects may include: flushing (sudden warmth, redness, or tingly feeling); upset stomach, vomiting, diarrhea; abnormal liver function tests; itching, dry skin; cough; skin discoloration; or headache. Sometimes, this increase in blood sugar gets better once a stable niacin dose is reached, although this is not always the case. All generic drug interactions for niacin oral (lists will include brand and generic names): 14 serious drug interactions; 37 significant drug interactions; 31 minor drug interactions; Patients and Caregivers; Clinician Explanation; Minor Interaction is unlikely, minor, or nonsignificant . Privacy Policy, Isosorbide mononitrate (Imdur, Ismo, Monoket), Atorvastatin (Lipitor) or other drugs containing atorvastatin, Lovastatin (Altoprev, Mevacor) or other drugs containing lovastatin, Simvastatin (Zocor) or other drugs containing simvastatin. If you’re one of these medications, then you should take them to six hours before taking niacin. Taking niacin with alcohol might increase the risk of liver damage and worsen niacin side effects, such as flushing and itching. Niacin Drug Interactions If alcoholic beverages or certain medications are combined with niacin, drug interactions could occur. This information should not be interpreted without the help of a healthcare provider. Usually avoid combinations; use it only under special circumstances. Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, ... Drug Interactions . Allopurinol (Zyloprim). Some mixtures of medications can lead to serious and even fatal consequences. Lovastatin. Antihypertensive Therapy . Nicotinic Acid (niacin) drug interactions. 3. Type in a drug name to check for interactions with niacin. Niacin can increase blood sugar, especially at high doses (like the niacin dosage used to improve cholesterol). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Rhabdomyolysis is a relatively uncommon condition in which muscle cells are broken down, releasing enzymes and electrolytes into the blood, and sometimes resulting in kidney failure .Co-administration of nicotinic acid with a statin seems to enhance the risk … Niacin can cause a severe allergic reaction. For patients taking both medications, more frequent INR monitoring than that which drug interaction references suggest may be advised. niacin ↔ Nicotine. Another important drug interaction occurs between statins and niacin and fibric acids, for example, gemfibrozil (Lopid), clofibrate (Atromid-S), and fenofibrate (Tricor). Another important drug interaction occurs between statins and niacin and fibric acids, for example, gemfibrozil , clofibrate (Atromid-S), and fenofibrate . Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. There are 96 drug interactions with niacin. Interactions with antidysrhythmics, tricyclic antidepressants and phenothiazines be corrected through modification of hypoglycemic.. The latest medication news, new drug approvals, alerts and updates the occurrence of rhabdomyolysis is increased in treated! May increase your risk of side effects if taken together, bleeding time should be closely.! The help of a healthcare provider immediately, such as acenocoumarol, warfarin ) niacin interactions! Accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products show all medications the! 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